New sesquiterpene hydroquinones from the Caribbean sponge Aka coralliphagum

New sesquiterpene hydroquinones from the Caribbean sponge Aka coralliphagum

Four new sulfated sesquiterpene hydroquinones siphonodictyals E1-E4 (1-4) and cyclosiphonodictyol A (5) were isolated from a sample of the Caribbean sponge Aka coralliphagum collected off the coast of San Salvador in the Bahamas. The structures of the new compounds were elucidated on the basis of mass spectrometric and NMR spectroscopic analysis. Compounds 1-4 are derivatives of siphonodictyal ...

Bioactive metabolites from the Caribbean sponge Aka coralliphagum.

The chemistry of the burrowing sponge Aka coralliphagum was investigated to identify chemically labile secondary metabolites. The HPLC-MS analysis of the two growth forms typica and incrustans revealed different metabolites. The previously unknown sulfated compounds siphonodictyals B1 to B3 (6-8), corallidictyals C (9) and D (10), and siphonodictyal G (11) were isolated, and their structures we...

A New Antibiotic Chloro-Sesquiterpene from the Caribbean Sponge Smenospongia aurea

Anna Aiello, Ernesto Fattorusso*, and Marialuisa Menna Dipartimento di Chimica delle Sostanze Naturali, Via D. Montesano 49, 1-80131 Napoli, Italy Z. Naturforsch. 48b, 209-212(1993); received September 18. 1992 Spongidae, Smenospongia aurea, Sesquiterpene, Antibiotic, NM R Spectra A new sesquiterpene phenol, containing the rather uncommon chlorine atom, was isolated from a sample of Smenospongi...

novel aromatic sesquiterpene from the sponge halichondria

Synthesis and Bioactivity of a Cyclopolypeptide from Caribbean Marine Sponge

Synthesis of a natural proline-rich cyclopolypeptide - rolloamide A [8] was carried out by coupling of tri- and tetrapeptide units Boc-Phe-Pro-Val-OMe and Boc-Pro-Leu-Pro-Ile-OMe after proper deprotection at carboxyl and amino terminals using carbodiimide chemistry in alkaline environment followed by cyclization of linear heptapeptide segment in the presence of base. The structure of synthesize...